ALENDRONATO EN OSTEOPOROSIS PDF

What Is Fosamax? They are the most commonly prescribed medications for the prevention and treatment of osteoporosis. These medications work by preventing the breakdown of bones and increasing bone density. They also decrease the risk of spine and hip fractures. There have been reports that some people who take Fosamax have developed a serious condition called osteonecrosis of the jaw, a condition in which bone tissue in the jaw dies, causing pain and the possible collapse of the jaw bone. When reports first started coming in, it created a lot of buzz on the Internet and it does sound scary.

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Warnings and Precautions: Atypical femur fractures have been reported with the use of bisphosphonates. Patients usually develop pain in the thigh or groin weeks or months prior to the development of fractures. Patients should also be evaluated for fracture of the opposite limb as well.

The patient may experience severe debilitating pain after the initiation of bisphosphonate therapy. Therapy may need to be interrupted. The patient may develop dysphagia, erosive esophagitis, and esophageal strictures. Patients who can not sit upright or have anatomical esophageal defects like achalasia of cardia should avoid using oral alendronate. Severe hypocalcemia may occur with the use of alendronate.

Calcium supplements should be added to the therapy. The patient may notice eye redness and swelling, conjunctivitis and uveitis. Ophthalmology consultation may be required.

The AAOMS American Association of maxillofacial surgeons recommends withholding bisphosphonate therapy two months prior to a dental procedure in patients who have been taking it for more than 4 years.

Furthermore, patients who have been taking it for less than 4 years but on concomitant steroids should also withhold alendronate therapy. For how long should alendronate be taken? Alendronate should be advised to postmenopausal women for at least five years who are at low risk of fracture and for at least ten years who are at high risk of fractures.

The optimal treatment duration in men is not known, however, the above recommendations may be followed in older men as well. Patients whose diet is deficient in calcium and vitamin D should also be advised supplements containing adequate calcium and vitamin D. The once-weekly formulation should be preferred as it is easily tolerated with better compliance.

For the treatment of osteoporosis: 10 mg once daily or 70 mg once weekly. It is not recommended for pregnant women and those who plan to become pregnant. The patient should be advised to take the dose the next morning and then resume on the scheduled day.

Two doses on the same day should be avoided.

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Efectos secundarios de Alendronato Sódico

Report Nancy, I also had side effects from Fosamax. Symptoms of hip and leg pain started after 3 months on it - mostly on left side. It got so bad that I could not sleep or lie down comfortably due to the pain, no matter what position I was in, on my back, side, etc. At 3 months in, I tried Aleve for 3 weeks to help, but the pain never went away. Finally I decided to stop the Fosamax after being on it for 6 months, but still had the pain.

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Is It Safe to Take Fosamax to Treat Osteoporosis?

Side effects[ edit ] Gastrointestinal tract: Ulceration and possible rupture of the esophagus ; this may require hospitalization and intensive treatment. Gastric and duodenal ulceration may also occur. Esophageal cancer , a meta-analysis concluded that bisphosphonate treatment is not associated with excess risk of esophageal cancer. In laboratory tests, decreased calcium and phosphate values may be seen but reflect expected action of the drug and are almost always not clinically relevant. Osteonecrosis of the jaw deterioration of the temporomandibular joint or TMJ may occur while on this drug, if dental work of any kind is carried out.

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